TargetMol

MT 63-78

Product Code:
 
TAR-T16156
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16156-1mg1mg£133.00
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TAR-T16156-2mg2mg£160.00
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TAR-T16156-5mg5mg£209.00
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TAR-T16156-1mL1 mL * 10 mM (in DMSO)£226.00
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TAR-T16156-10mg10mg£303.00
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TAR-T16156-25mg25mg£463.00
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TAR-T16156-50mg50mg£621.00
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TAR-T16156-100mg100mg£849.00
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Further Information

Bioactivity:
MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63?78 also causes cell mitotic arrest and apoptosis.
CAS:
1179347-65-9
Formula:
C21H14N2O2
Molecular Weight:
326.355
Pathway:
Apoptosis; PI3K/Akt/mTOR signaling; Chromatin/Epigenetic
Purity:
0.9803
SMILES:
Oc1cccc(O)c1-c1ccc(cc1)-c1ccc2[nH]cc(C#N)c2c1
Target:
Apoptosis; AMPK; mTOR

References

1. Zadra G, et al. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014 Apr;6(4):519-38.