TargetMol

UNC2541

Product Code:
 
TAR-T17205
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17205-2mg2mg£104.00
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TAR-T17205-5mg5mg£125.00
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TAR-T17205-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T17205-10mg10mg£158.00
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TAR-T17205-25mg25mg£258.00
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TAR-T17205-50mg50mg£351.00
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Further Information

Bioactivity:
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
CAS:
1612782-86-1
Formula:
C24H34FN7O2
Molecular Weight:
471.581
Pathway:
; Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9946
SMILES:
N[C@H]1CCCCNc2nc(NCCCCCCNC1=O)ncc2C(=O)NCc1ccc(F)cc1
Target:
FLT; TAM Receptor

References

1. McIver AL, et al. Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors. ChemMedChem. 2017 Feb 3;12(3):207-213.