TargetMol

MCOPPB triHydrochloride

Product Code:
 
TAR-T2071
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2071-1mg1mg£98.00
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TAR-T2071-2mg2mg£109.00
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TAR-T2071-5mg5mg£132.00
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TAR-T2071-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T2071-10mg10mg£179.00
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TAR-T2071-25mg25mg£293.00
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TAR-T2071-50mg50mg£430.00
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TAR-T2071-100mg100mg£600.00
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Further Information

Bioactivity:
MCOPPB trihydrochlride is a nociceptin receptor agonist.
CAS:
1108147-88-1
Formula:
C26H43Cl3N4
Molecular Weight:
518.01
Pathway:
Endocrinology/Hormones; Neuroscience; GPCR/G Protein
Purity:
0.9991
SMILES:
Cl.Cl.Cl.CC1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)[C@@H]1CCCNC1
Target:
Opioid Receptor

References

1. Hayashi, Shigeo; Hirao, Akiko; Imai, Aki; Nakamura, Hiroshi; Murata, Yoshinori; Ohashi, Katsuyo; Nakata, Eriko. Novel Non-Peptide Nociceptin/Orphanin FQ Receptor Agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: Design, Synthesis, and Structure-Activity Relationship of Oral Receptor Occupancy in the Brain for Orally Potent Antianxiety Drug. Journal of Medicinal Chemistry (2009), 52(3), 610-625. 2. Hayashi S, Hirao A, Imai A, Nakamura H, Murata Y, Ohashi K, Nakata E.Novel non-peptide nociceptin/orphanin FQ receptor agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: design, synthesis, and structure-activity relationship of oral receptor occupancy in the brain for orally potent antianxiety drug.J Med Chem. 2009 Feb 12;52(3):610-25. 3. Hirao A, Imai A, Sugie Y, Yamada Y, Hayashi S, Toide K.Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent.J Pharmacol Sci. 2008 Mar;106(3):361-8. Epub 2008 Mar 5.