TargetMol

A 438079 hydrochloride

Product Code:
 
TAR-T2673
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T2673-2mg2mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2673-5mg5mg£124.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2673-10mg10mg£155.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2673-1mL1 mL * 10 mM (in DMSO)£164.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2673-25mg25mg£222.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2673-50mg50mg£321.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2673-100mg100mg£510.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
A-438079 hydrochloride is a potent and selective P2X7 receptor antagonist with pIC50 of 6.9.
CAS:
899431-18-6
Formula:
C13H10Cl3N5
Molecular Weight:
342.61
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.9974
SMILES:
Cl.Clc1cccc(-c2nnnn2Cc2cccnc2)c1Cl
Target:
P2X Receptor

References

1. McGaraughty S, et al. Neuroscience. 2007, 146(4), 1817-1828. 2. Mesuret G, et al. CNS Neurosci Ther. 2014, 20(6), 556-564. 3. Marcellino D, et al. J Neural Transm. 2010, 17(6), 681-687. 4. Martins JP, et al. Br J Pharmacol. 2012, 165(1), 183-196. 5. Su Q, Tian Y, Liu Z, et al. Purinergic P2X7 receptor blockade mitigates alcohol-induced steatohepatitis and intestinal injury by regulating MEK1/2-ERK1/2 signaling and egr-1 activity[J]. International immunopharmacology. 2019 Jan;66:52-61.