TargetMol

PF-04217903

Product Code:
 
TAR-T2676
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2676-1mg1mg£96.00
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Quantity:
TAR-T2676-2mg2mg£107.00
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TAR-T2676-5mg5mg£124.00
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TAR-T2676-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T2676-10mg10mg£149.00
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Quantity:
TAR-T2676-25mg25mg£215.00
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Quantity:
TAR-T2676-50mg50mg£314.00
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Quantity:
TAR-T2676-100mg100mg£511.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity.
CAS:
956905-27-4
Formula:
C19H16N8O
Molecular Weight:
372.392
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9855
SMILES:
OCCn1cc(cn1)-c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1
Target:
c-Met/HGFR

References

1. Timofeevski SL, et al. Biochemistry, 2009, 48(23), 5339-5349. 2. Shojaei F, et al. Cancer Res, 2010, 70(24), 120090-120100. 3. Krumbach R, et al. Eur J Cancer, 2011, 47(8), 1231-1243. 4. Dillon R, et al. J Proteome Res, 2011, 10(11), 5084-5094. 5. Gui Y, Lu Q, Gu M, et al. Fibroblast mTOR/PPAR?/HGF axis protects against tubular cell death and acute kidney injury[J]. Cell Death & Differentiation. 2019 Apr 25.