TargetMol

Xevinapant hydrochloride

Product Code:
 
TAR-T3299
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3299-5mg5mg£134.00
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TAR-T3299-10mg10mg£170.00
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TAR-T3299-1mL1 mL * 10 mM (in DMSO)£230.00
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TAR-T3299-25mg25mg£298.00
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TAR-T3299-50mg50mg£505.00
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This product comes from: United States.
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Further Information

Bioactivity:
AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.
CAS:
1071992-57-8
Formula:
C32H44ClN5O4
Molecular Weight:
598.19
Pathway:
Apoptosis
Purity:
0.98
SMILES:
Cl.CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C
Target:
Apoptosis; IAP

References

1. Cai Q, et al. J Med Chem, 2011, 54(8), 2714-2726.