TargetMol

AKT inhibitor VIII

Product Code:
 
TAR-T3346
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3346-1mg1mg£106.00
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TAR-T3346-2mg2mg£119.00
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TAR-T3346-5mg5mg£156.00
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TAR-T3346-1mL1 mL * 10 mM (in DMSO)£174.00
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TAR-T3346-10mg10mg£195.00
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TAR-T3346-25mg25mg£294.00
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TAR-T3346-50mg50mg£436.00
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TAR-T3346-100mg100mg£610.00
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This product comes from: United States.
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Further Information

Bioactivity:
AKT inhibitor VIII is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.
CAS:
612847-09-3
Formula:
C34H29N7O
Molecular Weight:
551.654
Pathway:
Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Apoptosis
Purity:
0.9865
SMILES:
O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3cc4[nH]cnc4cc3nc2-c2ccccc2)CC1
Target:
Apoptosis; Akt

References

Lindsley CW, et al. Bioorg Med Chem Lett. 2005, 15(3), 761-764. Hunter RW, et al. J Thromb Haemost. 2008, 6(11), 1923-1932. Puglisi M, et al. Lung Cancer. 2014, 85(2), 141-146. Logie L, et al. Diabetes. 2007, 56(9), 2218-2227.