TargetMol

BFH772

Product Code:
 
TAR-T3599
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3599-2mg2mg£101.00
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TAR-T3599-5mg5mg£119.00
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TAR-T3599-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T3599-10mg10mg£155.00
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TAR-T3599-25mg25mg£230.00
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TAR-T3599-50mg50mg£309.00
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TAR-T3599-100mg100mg£523.00
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Further Information

Bioactivity:
BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM.
CAS:
890128-81-1
Formula:
C23H16F3N3O3
Molecular Weight:
439.394
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9771
SMILES:
OCc1cc(Oc2ccc3c(cccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1
Target:
VEGFR

References

Bold G, et al. J Med Chem. 2016, 59(1):132-46.