TargetMol

Cyasterone

Product Code:
 
TAR-T3870
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3870-1mg1mg£95.00
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TAR-T3870-5mg5mg£122.00
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TAR-T3870-10mg10mg£161.00
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TAR-T3870-25mg25mg£242.00
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TAR-T3870-50mg50mg£327.00
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TAR-T3870-100mg100mg£452.00
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This product comes from: United States.
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Further Information

Bioactivity:
Cyasterone, a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising anti-cancer agent. Cyasterone has antifeeding activity.
CAS:
17086-76-9
Formula:
C29H44O8
Molecular Weight:
520.663
Pathway:
Angiogenesis; JAK/STAT signaling; Apoptosis; Tyrosine Kinase/Adaptors
Purity:
0.9932
SMILES:
C[C@H]1OC(=O)[C@@H](C)[C@@H]1C[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C
Target:
Apoptosis; EGFR

References

Hirayama Y,et al. Stereochemical assignment of C-24 and C-25 of amarasterone A, a putative biosynthetic intermediate of cyasterone. J Org Chem. 2014 Jun 20;79(12):5471-7. Lu X,et al. Anti-proliferation effects, efficacy of cyasterone in vitro and in vivo and its mechanism. Biomed Pharmacother. 2016 Dec;84:330-339.