TargetMol

Ginsenoside Rb3

Product Code:
 
TAR-T3918
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3918-5mg5mg£95.00
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TAR-T3918-10mg10mg£115.00
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TAR-T3918-25mg25mg£144.00
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TAR-T3918-50mg50mg£177.00
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TAR-T3918-100mg100mg£229.00
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Further Information

Bioactivity:
Ginsenoside Rb3 is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA.
CAS:
68406-26-8
Formula:
C53H90O22
Molecular Weight:
1079.281
Pathway:
NF-κb; Immunology/Inflammation; Neuroscience
Purity:
0.9998
SMILES:
CC(C)=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@@H]3CC[C@@]21C
Target:
NF-κB; COX; NO Synthase

References

Wang Y, et al. Ginsenoside Rb3 attenuates oxidative stress and preserves endothelial function in renal arteries from hypertensive rats. Br J Pharmacol. 2014 Jul;171(13):3171-81. Ma L, et al. Ginsenoside Rb3 protects cardiomyocytes against ischemia-reperfusion injury via the inhibition of JNK-mediated NF-?B pathway: a mouse cardiomyocyte model. PLoS One. 2014 Aug 1;9(8):e103628. Zhu JR, et al. Protective effects of ginsenoside Rb(3) on oxygen and glucose deprivation-induced ischemic injury in PC12 cells. Acta Pharmacol Sin. 2010 Mar;31(3):273-80. Wang T, et al. Ginsenoside Rb3 inhibits angiotensin II-induced vascular smooth muscle cells proliferation. Basic Clin Pharmacol Toxicol. 2010 Aug;107(2):685-9.