TargetMol

Hydroxyfasudil Hydrochloride

Product Code:
 
TAR-T4276
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4276-2mg2mg£98.00
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TAR-T4276-5mg5mg£115.00
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TAR-T4276-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T4276-10mg10mg£138.00
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TAR-T4276-25mg25mg£173.00
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TAR-T4276-50mg50mg£195.00
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TAR-T4276-100mg100mg£302.00
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This product comes from: United States.
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Further Information

Bioactivity:
Hydroxyfasudil hydrochloride is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).
CAS:
155558-32-0
Formula:
C14H18ClN3O3S
Molecular Weight:
343.83
Pathway:
Cytoskeletal Signaling; Stem Cells; Cell Cycle/Checkpoint
Purity:
0.9982
SMILES:
Cl.O=c1[nH]ccc2c(cccc12)S(=O)(=O)N1CCCNCC1
Target:
ROCK

References

Sun L, Sun L, Li X, et al. A Novel Tigecycline Adjuvant ML-7 Reverses the Susceptibility of Tigecycline-Resistant Klebsiella pneumoniae. Frontiers in cellular and infection microbiology. 2022: 1341. Saito M, et al. Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat. Pharmacol Res. 2012 Oct;66(4):325-31. Rikitake Y, et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct;36(10):2251-7. Epub 2005 Sep 1. Masago T, et al. Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: an experimental rat model. Int J Urol. 2009 Oct;16(10):842-7.