TargetMol

NS 11021

Product Code:
 
TAR-T4294
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4294-1mg1mg£138.00
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TAR-T4294-2mg2mg£168.00
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TAR-T4294-5mg5mg£230.00
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TAR-T4294-1mL1 mL * 10 mM (in DMSO)£254.00
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TAR-T4294-10mg10mg£334.00
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TAR-T4294-25mg25mg£515.00
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TAR-T4294-50mg50mg£704.00
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TAR-T4294-100mg100mg£930.00
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Further Information

Bioactivity:
NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels
CAS:
956014-19-0
Formula:
C16H9BrF6N6S
Molecular Weight:
511.24
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
FC(F)(F)c1cc(NC(=S)Nc2ccc(Br)cc2-c2nnn[nH]2)cc(c1)C(F)(F)F
Target:
Potassium Channel

References

Bentzen BH, et al. The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels. Mol Pharmacol. 2007 Oct;72(4):1033-44. Kun A , Matchkov V V , Stankevicius E , et al. NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats[J]. British Journal of Pharmacology, 2010, 158(6):1465-1476.