TargetMol

iCRT3

Product Code:
 
TAR-T4302
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4302-2mg2mg£102.00
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TAR-T4302-5mg5mg£122.00
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TAR-T4302-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T4302-10mg10mg£148.00
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TAR-T4302-25mg25mg£221.00
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TAR-T4302-50mg50mg£306.00
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TAR-T4302-100mg100mg£454.00
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TAR-T4302-500mg500mg£914.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.
CAS:
901751-47-1
Formula:
C23H26N2O2S
Molecular Weight:
394.53
Pathway:
Cytoskeletal Signaling; Stem Cells; Apoptosis
Purity:
0.9832
SMILES:
CCc1ccc(cc1)-c1nc(CSCC(=O)NCCc2ccccc2)c(C)o1
Target:
Apoptosis; Wnt/beta-catenin

References

Sharma A, et al. Mitigation of sepsis-induced inflammatory responses and organ injury through targeting Wnt/?-catenin signaling. doi: 10.1038/s41598-2017-08711-6. Wang J, Gong L, Zhang W, et al. Wnt/?-catenin signaling pathway inhibits porcine reproductive and respiratory syndrome virus replication by enhancing the nuclear factor-?B-dependent innate immune response[J]. Veterinary Microbiology . 2020: 108904. Chatterjee SS, et al. Inhibition of ?-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells. J Cell Biol. 2015 Oct 12;211(1):39-51. Xiao H, et al. A Novel Positive Feedback Loop Between NTSR1 and Wnt/?-Catenin Contributes to Tumor Growth of Glioblastoma. Cell Physiol Biochem. 2017 Oct 24;43(5):2133-2142. Wang J, Gong L, Zhang W, et al. Wnt/?-catenin signaling pathway inhibits porcine reproductive and respiratory syndrome virus replication by enhancing the nuclear factor-?B-dependent innate immune response. Veterinary Microbiology. 2020: 108904.