TargetMol

SPDB

Product Code:
 
TAR-T4346
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4346-2mg2mg£108.00
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Quantity:
TAR-T4346-1mL1 mL * 10 mM (in DMSO)£140.00
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Quantity:
TAR-T4346-5mg5mg£140.00
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Quantity:
TAR-T4346-10mg10mg£166.00
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Quantity:
TAR-T4346-50mg50mg£295.00
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Quantity:
TAR-T4346-100mg100mg£375.00
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Quantity:
TAR-T4346-200mg200mg£550.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SPDB is a small fragment linked to DM4 conjugates. It conjugates to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used.
CAS:
115088-06-7
Formula:
C13H14N2O4S2
Molecular Weight:
326.39
Purity:
0.9543
SMILES:
O=C(CCCSSc1ccccn1)ON1C(=O)CCC1=O

References

Widdison WC et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolitesin Cancer Cells andInduce High Levels of Bystander Killing. Bioconjug Chem, 2015 Nov 18, 26(11):2261-78.