TargetMol

CGP52432

Product Code:
 
TAR-T4363
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4363-1mg1mg£98.00
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TAR-T4363-2mg2mg£109.00
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TAR-T4363-5mg5mg£134.00
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TAR-T4363-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T4363-10mg10mg£185.00
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TAR-T4363-25mg25mg£295.00
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TAR-T4363-50mg50mg£460.00
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TAR-T4363-100mg100mg£645.00
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Further Information

Bioactivity:
CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).
CAS:
139667-74-6
Formula:
C15H24Cl2NO4P
Molecular Weight:
384.23
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9916
SMILES:
CCOC(OCC)P(O)(=O)CCCNCc1ccc(Cl)c(Cl)c1
Target:
GABA Receptor

References

Lanza M,etal.CGP 52432: a novel potent and selective GABAB autoreceptor antagonist in rat cerebral cortex.Eur J Pharmacol. 1993 Jun 24;237(2-3):191-5. Bonanno G,etal.GABA(B) receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord.Eur J Pharmacol. 1998 Dec 4;362(2-3):143-8. Libri V,etal.Blockade of GABA(B) receptors facilitates muscarinic agonist-induced epileptiform activity in immature rat piriform cortex in vitro.Naunyn Schmiedebergs Arch Pharmacol. 1998 Aug;358(2):168-74.