TargetMol

AX-024 hydrochloride

Product Code:
 
TAR-T4403
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4403-1mg1mg£112.00
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TAR-T4403-2mg2mg£131.00
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TAR-T4403-5mg5mg£164.00
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TAR-T4403-1mL1 mL * 10 mM (in DMSO)£181.00
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TAR-T4403-10mg10mg£214.00
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TAR-T4403-25mg25mg£405.00
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TAR-T4403-50mg50mg£568.00
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TAR-T4403-100mg100mg£777.00
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This product comes from: United States.
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Further Information

Bioactivity:
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
CAS:
1704801-24-0
Formula:
C21H23ClFNO2
Molecular Weight:
375.87
Pathway:
Immunology/Inflammation; Apoptosis; Neuroscience
Purity:
0.999
SMILES:
Cl.COc1ccc2OCC(CN3CCCC3)=C(c3ccc(F)cc3)c2c1
Target:
IL Receptor; TNF; COX; IFNAR; Interleukin

References

Borroto A, etal. First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases. Sci Transl Med. 2016 Dec 21;8(370):370ra184.