TargetMol

SR17018

Product Code:
 
TAR-T4407
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4407-5mg5mg£122.00
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TAR-T4407-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T4407-10mg10mg£148.00
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TAR-T4407-25mg25mg£242.00
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TAR-T4407-50mg50mg£349.00
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TAR-T4407-100mg100mg£523.00
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Quantity:
TAR-T4407-200mg200mg£702.00
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This product comes from: United States.
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Further Information

Bioactivity:
SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
CAS:
2134602-45-0
Formula:
C19H18Cl3N3O
Molecular Weight:
410.72
Pathway:
Neuroscience; Endocrinology/Hormones; GPCR/G Protein
Purity:
0.9973
SMILES:
Clc1ccc(CN2CCC(CC2)n2c3cc(Cl)c(Cl)cc3[nH]c2=O)cc1
Target:
Opioid Receptor

References

Zhuang Y, Wang Y, He B, et al. Molecular recognition of morphine and fentanyl by the human ?-opioid receptor. Cell. 2022, 185(23): 4361-4375. e19. Schmid CL,etal.Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics.Cell. 2017 Nov 16;171(5):1165-1175.