TargetMol

(-)-Blebbistatin

Product Code:
 
TAR-T6038
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6038-2mg2mg£100.00
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TAR-T6038-5mg5mg£119.00
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TAR-T6038-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T6038-10mg10mg£149.00
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TAR-T6038-25mg25mg£229.00
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TAR-T6038-100mg100mg£491.00
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Further Information

Bioactivity:
(-)-Blebbistatin is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.
CAS:
856925-71-8
Formula:
C18H16N2O2
Molecular Weight:
292.338
Pathway:
Membrane transporter/Ion channel; Cytoskeletal Signaling
Purity:
0.9959
SMILES:
Cc1ccc2N=C3N(CC[C@@]3(O)C(=O)c2c1)c1ccccc1
Target:
ATPase; Myosin

References

Zhang X, et al. In vitro and in vivo relaxation of urinary bladder smooth muscle by the selective myosin IIinhibitor, blebbistatin. BJU Int. 2011 Jan;107(2):310-7. Kov?cs M, et al. J Biol Chem, 2004, 279(34), 35557-35563 Limouze J, et al. J Muscle Res Cell Motil, 2004, 25(4-5), 337-341. Straight AF, et al. Science, 2003, 299(5613), 1743-1747. Tian X, Gao M, Li A, et al. Protocol for Isolation of Viable Adult Rat Cardiomyocytes with High Yield[J]. STAR Protocols. 2020: 100045.