TargetMol

PD 123319

Product Code:
 
TAR-T6067
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T6067-1mg1mg£107.00
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TAR-T6067-2mg2mg£121.00
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TAR-T6067-5mg5mg£169.00
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TAR-T6067-1mL1 mL * 10 mM (in DMSO)£198.00
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TAR-T6067-10mg10mg£222.00
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TAR-T6067-25mg25mg£380.00
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TAR-T6067-50mg50mg£472.00
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TAR-T6067-100mg100mg£593.00
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Quantity:
TAR-T6067-500mg500mg£1,187.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist.
CAS:
130663-39-7
Formula:
C31H32N4O3
Molecular Weight:
508.622
Pathway:
Endocrinology/Hormones
Purity:
0.9861
SMILES:
CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C
Target:
RAAS

References

Tamura M, et al. J Hypertens, 2000, 18(9), 1239-1246. Zhang L, Zhang B, Yu Y, et al. Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload[J]. International Heart Journal. 2021: 20-384 Estrup TM, et al. J Renin Angiotensin Aldosterone Syst, 2001, 2(3), 188-192. Boulay G, et al. Mol Pharmacol, 1992, 41(4), 809-815. Blankley CJ, et al. J Med Chem, 1991, 34(11), 3248-3260. Zhang L, Zhang B, Yu Y, et al. Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload. International Heart Journal. 2021: 20-384