TargetMol

SU11274

Product Code:
 
TAR-T6154
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6154-1mg1mg£102.00
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TAR-T6154-2mg2mg£114.00
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TAR-T6154-5mg5mg£149.00
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TAR-T6154-1mL1 mL * 10 mM (in DMSO)£193.00
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TAR-T6154-10mg10mg£193.00
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TAR-T6154-25mg25mg£309.00
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TAR-T6154-50mg50mg£464.00
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TAR-T6154-100mg100mg£653.00
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This product comes from: United States.
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Further Information

Bioactivity:
SU11274(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.
CAS:
658084-23-2
Formula:
C28H30ClN5O4S
Molecular Weight:
568.09
Pathway:
Autophagy; Apoptosis; Tyrosine Kinase/Adaptors; Angiogenesis; Cell Cycle/Checkpoint
Purity:
0.9862
SMILES:
CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2NC(=O)C(=C/c3[nH]c(C)c(C(=O)N4CCN(C)CC4)c3C)c2c1
Target:
Apoptosis; VEGFR; FGFR; c-Met/HGFR; CDK; Autophagy

References

Wang X, et al. Mol Cancer Ther, 2003, 2(11):1085-1092. Sattler M, et al. Cancer Res, 2003, 63(17), 5462-5469. Ma PC, et al. Cancer Res, 2005, 65(4), 1479-1488.