TargetMol

CCT129202

Product Code:
 
TAR-T6435
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6435-1mg1mg£102.00
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TAR-T6435-2mg2mg£114.00
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TAR-T6435-5mg5mg£136.00
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TAR-T6435-10mg10mg£191.00
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TAR-T6435-25mg25mg£283.00
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TAR-T6435-50mg50mg£412.00
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TAR-T6435-100mg100mg£575.00
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Quantity:
TAR-T6435-500mg500mg£1,155.00
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Quantity:
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Further Information

Bioactivity:
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
CAS:
942947-93-5
Formula:
C23H25ClN8OS
Molecular Weight:
497.02
Pathway:
Chromatin/Epigenetic; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
CN(C)c1ccc(cc1)-c1nc2ncc(Cl)c(N3CCN(CC(=O)Nc4nccs4)CC3)c2[nH]1
Target:
Aurora Kinase

References

Chan F, et al. Mol Cancer Ther. 2007, 6(12), 3147-3157.