TargetMol

Hesperadin

Product Code:
 
TAR-T6532
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6532-2mg2mg£97.00
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TAR-T6532-5mg5mg£112.00
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TAR-T6532-1mL1 mL * 10 mM (in DMSO)£118.00
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TAR-T6532-10mg10mg£132.00
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TAR-T6532-25mg25mg£173.00
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TAR-T6532-50mg50mg£237.00
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Further Information

Bioactivity:
Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK1 activity in vivo.
CAS:
422513-13-1
Formula:
C29H32N4O3S
Molecular Weight:
516.66
Pathway:
Microbiology/Virology; Cell Cycle/Checkpoint; Autophagy; Chromatin/Epigenetic
Purity:
0.9944
SMILES:
CCS(=O)(=O)Nc1ccc2NC(=O)C(=C(/Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)c2c1
Target:
Influenza Virus; Parasite; Aurora Kinase; Autophagy

References

Hauf S, et al. J Cell Biol, 2003, 161(2), 281-294. Wang J, Yan X, Chen H, et al. Enhanced UV-B radiation affects AUR1 regulation of mitotic spindle morphology leading to aberrant mitosis. Plant Physiology and Biochemistry. 159: 160-170. Jetton N, et al. Mol Microbiol, 2009, 72(2), 442-458. Wang J, Yan X, Chen H, et al. Enhanced UV-B radiation affects AUR1 regulation of mitotic spindle morphology leading to aberrant mitosis[J]. Plant Physiology and Biochemistry. 159: 160-170.