TargetMol

XL413 hydrochloride

Product Code:
 
TAR-T6735
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6735-1mg1mg£124.00
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TAR-T6735-5mg5mg£193.00
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TAR-T6735-10mg10mg£252.00
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TAR-T6735-25mg25mg£374.00
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TAR-T6735-50mg50mg£524.00
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TAR-T6735-100mg100mg£707.00
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TAR-T6735-200mg200mg£978.00
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Quantity:
TAR-T6735-500mg500mg£1,412.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS-863233 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. CDC7, a serine-threonine kinase overexpressed in a variety of tumor cell types, plays an essential role in the initiation of DNA replication by activating origins of replication.
CAS:
1169562-71-3
Formula:
C14H13Cl2N3O2
Molecular Weight:
326.18
Pathway:
Chromatin/Epigenetic; GPCR/G Protein; JAK/STAT signaling; Metabolism; Cell Cycle/Checkpoint; Stem Cells
Purity:
0.9982
SMILES:
Cl.Clc1ccc2oc3c(nc([nH]c3=O)[C@@H]3CCCN3)c2c1
Target:
cholecystokinin; Casein Kinase; Pim; CDK

References

Koltun ES, et al. Bioorg Med Chem Lett. 2012, 22(11), 3727-3731.