TargetMol

NM107

Product Code:
 
TAR-T7215
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7215-2mg2mg£100.00
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TAR-T7215-5mg5mg£118.00
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TAR-T7215-10mg10mg£136.00
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TAR-T7215-50mg50mg£198.00
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Quantity:
TAR-T7215-100mg100mg£230.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NM107 is a ribonucleoside with broad-spectrum antiviral activity, is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, NM 107 in the wild-type replicon cells with the EC50 of 1.85 μM
CAS:
20724-73-6
Formula:
C10H15N3O5
Molecular Weight:
257.246
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.98
SMILES:
C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc(N)nc1=O
Target:
HCV Protease

References

Guedj J , Dahari H , Rong L , et al. Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life[J]. Proceedings of the National Academy of Sciences, 2013, 110(10):3991-3996. Rochapereira J , Dycke J V , Neyts J . Treatment with a Nucleoside Polymerase Inhibitor Reduces Shedding of Murine Norovirus in Stool to Undetectable Levels without Emergence of Drug-Resistant Variants[J]. Antimicrobial Agents & Chemotherapy, 2015, 60(3):AAC.02198-15. Goris N , De Palma A , Toussaint, JeanFran?ois, et al. 2'-C-Methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus[J]. Antiviral Research, 2007, 73(3):161-168.