TargetMol

EB-3D

Product Code:
 
TAR-T7955
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7955-1mg1mg£145.00
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TAR-T7955-2mg2mg£177.00
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TAR-T7955-5mg5mg£229.00
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TAR-T7955-10mg10mg£303.00
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TAR-T7955-1mL1 mL * 10 mM (in DMSO)£305.00
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TAR-T7955-25mg25mg£470.00
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TAR-T7955-50mg50mg£653.00
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TAR-T7955-100mg100mg£863.00
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This product comes from: United States.
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Further Information

Bioactivity:
EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.
CAS:
1839150-63-8
Formula:
C30H36Br2N4O2
Molecular Weight:
644.452
Pathway:
Neuroscience; PI3K/Akt/mTOR signaling; Apoptosis; Chromatin/Epigenetic
Purity:
0.9875
SMILES:
[Br-].[Br-].CN(C)c1cc[n+](Cc2ccc(OCCOc3ccc(C[n+]4ccc(cc4)N(C)C)cc3)cc2)cc1
Target:
Apoptosis; AMPK; AChR

References

Schiaffino-Ortega S , Baglioni E , Mariotto E , et al. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase ?1 (ChoK?1)[J]. Scientific Reports, 2016, 6:23793. Elena M , Roberta B , Ilaria V , et al. EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR Pathway and apoptosis in leukemia T-cells[J]. Biochemical Pharmacology, 2018:S0006295218302727-.