TargetMol

BRD3308

Product Code:
 
TAR-T8233
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8233-1mg1mg£101.00
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TAR-T8233-2mg2mg£114.00
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TAR-T8233-5mg5mg£140.00
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TAR-T8233-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T8233-10mg10mg£173.00
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TAR-T8233-25mg25mg£258.00
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TAR-T8233-50mg50mg£353.00
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TAR-T8233-100mg100mg£495.00
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This product comes from: United States.
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Further Information

Bioactivity:
BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.
CAS:
1550053-02-5
Formula:
C15H14FN3O2
Molecular Weight:
287.294
Pathway:
Chromatin/Epigenetic; Microbiology/Virology; DNA Damage/DNA Repair; Proteases/Proteasome; Apoptosis
Purity:
0.9712
SMILES:
CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N
Target:
Apoptosis; HIV Protease; HDAC

References

Wagner FF, et al. An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in ?-Cell Protection. ACS Chem Biol. 2016 Feb 19;11(2):363-74. Lundh M, et al. Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats. Diabetes Obes Metab. 2015 Jul;17(7):703-7.