TargetMol

1V209

Product Code:
 
TAR-T8316
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8316-1mg1mg£96.00
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TAR-T8316-2mg2mg£107.00
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TAR-T8316-5mg5mg£128.00
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TAR-T8316-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T8316-10mg10mg£173.00
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TAR-T8316-25mg25mg£301.00
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TAR-T8316-50mg50mg£436.00
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TAR-T8316-100mg100mg£610.00
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This product comes from: United States.
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Further Information

Bioactivity:
1V209 is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.
CAS:
1062444-54-5
Formula:
C16H17N5O5
Molecular Weight:
359.34
Pathway:
Immunology/Inflammation
Purity:
0.9853
SMILES:
COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(cc3)C(O)=O)c2n1
Target:
TLR

References

Liang C, Xiong N, Liu M, et al.Manganese immunotherapy for treating osteosarcoma: Glycosylating 1V209 anchored MnO2 nanosheets prompt pro-inflammatory macrophage polarization.Nano Today.2023, 48: 101670. Shinchi H, et al. Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides. Bioconjug Chem. 2015 Aug 19;26(8):1713-23. Gold Nanoparticles Coimmobilized with Small Molecule Toll-Like Receptor 7 Ligand and ??Mannose as Adjuvants[J]. Bioconjugate Chemistry, 2019, 30(11):2811-2821. Battistella C, et al. Delivery of Immunotherapeutic Nanoparticles to Tumors via Enzyme-Directed Assembly. Adv Healthc Mater. 2019 Dec;8(23):e1901105.