TargetMol

SKF-83566

Product Code:
 
TAR-T8702
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T8702-100mg100mgEnquire
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TAR-T8702-50mg50mgEnquire
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Further Information

Bioactivity:
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM
CAS:
99295-33-7
Formula:
C17H18BrNO
Molecular Weight:
332.241
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.95
SMILES:
CN1CCc2cc(Br)c(O)cc2C(C1)c1ccccc1
Target:
Dopamine Receptor; 5-HT Receptor; AChR

References

Yan-You Huang, et al.D1/D5 Receptors and Histone Deacetylation Mediate the Gateway Effect of LTP in Hippocampal Dentate Gyrus. Melissa A Stouffer, et al. SKF-83566, a D1-dopamine Receptor Antagonist, Inhibits the Dopamine Transporter. J Neurochem. 2011 Sep;118(5):714-20. Yan-You Huang, et al. D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus. Learn Mem. 2014 Feb 18;21(3):153-60. doi: 10.1101/lm.032292.113.