TargetMol

FB23

Product Code:
 
TAR-T8874
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8874-1mg1mg£107.00
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TAR-T8874-2mg2mg£122.00
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TAR-T8874-5mg5mg£152.00
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TAR-T8874-1mL1 mL * 10 mM (in DMSO)£165.00
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TAR-T8874-10mg10mg£214.00
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TAR-T8874-25mg25mg£367.00
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TAR-T8874-50mg50mg£529.00
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TAR-T8874-100mg100mg£728.00
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Quantity:
TAR-T8874-500mg500mg£1,428.00
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Further Information

Bioactivity:
FB23 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. (FTO, an mRNA N6-methyladenosine (m6A) demethylase, was reported to promote leukemogenesis.)
CAS:
2243736-35-6
Formula:
C18H14Cl2N2O3
Molecular Weight:
377.22
Purity:
0.9822
SMILES:
Cc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(O)=O)c(Cl)c1

References

Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia[J]. Science Foundation in China, 2019.