TargetMol

NBI-31772

Product Code:
 
TAR-T8906
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8906-1mg1mg£111.00
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TAR-T8906-2mg2mg£130.00
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TAR-T8906-5mg5mg£168.00
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TAR-T8906-1mL1 mL * 10 mM (in DMSO)£214.00
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TAR-T8906-10mg10mg£229.00
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TAR-T8906-25mg25mg£414.00
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TAR-T8906-50mg50mg£584.00
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TAR-T8906-100mg100mg£785.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
NBI-31772 is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM). NBI-31772 can be used in research on IGF-responsive diseases.
CAS:
374620-70-9
Formula:
C17H11NO7
Molecular Weight:
341.275
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9983
SMILES:
OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1
Target:
IGF-1R

Documents

References

Safian D, et al. Follicle-Stimulating Hormone Regulates igfbp Gene Expression Directly or via Downstream Effectors to Modulate Igf3 Effects on Zebrafish Spermatogenesis. Front Endocrinol (Lausanne). 2017 Nov 20;8:328. Rinker TE, et al. Microparticle-mediated sequestration of cell-secreted proteins to modulate chondrocytic differentiation. Acta Biomater. 2017 Dec 30. pii: S1742-7061(17)30804-8. L?k? AH, et al. Insulin-like growth factor I and its binding protein-3 are regulators of lactation and maternal responsiveness. Sci Rep. 2017 Jun 13;7(1):3396. Safian D, et al. Igf Binding Proteins Protect Undifferentiated Spermatogonia in the Zebrafish Testis Against Excessive Differentiation. Endocrinology. 2016 Nov;157(11):4423-4433. Epub 2016 Sep 30.