TargetMol

TJ-M2010-5

Product Code:
 
TAR-T9765
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9765-1mg1mg£95.00
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TAR-T9765-2mg2mg£106.00
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TAR-T9765-5mg5mg£128.00
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TAR-T9765-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T9765-10mg10mg£161.00
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TAR-T9765-25mg25mg£262.00
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TAR-T9765-50mg50mg£369.00
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TAR-T9765-100mg100mg£530.00
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TAR-T9765-200mg200mg£725.00
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Further Information

Bioactivity:
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
CAS:
1357471-57-8
Formula:
C23H26N4OS
Molecular Weight:
406.54
Pathway:
Immunology/Inflammation
Purity:
0.9701
SMILES:
O=C(NC1=NC(C2=CC=CC=C2)=CS1)CCN3CCN(CC4=CC=CC=C4)CC3
Target:
MyD88

References

Lin Xie, et al. Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer. J Natl Cancer Inst. 2015 Dec 28;108(4):djv364. Yan Miao,et al. Inhibition of MyD88 by a novel inhibitor reverses two-thirds of the infarct area in myocardial ischemia and reperfusion injury.Am J Transl Res. 2020 Sep 15;12(9):5151-5169.