TargetMol

Sacubitrilat

Product Code:
 
TAR-TQ0106
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0106-1mg1mg£103.00
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TAR-TQ0106-2mg2mg£116.00
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TAR-TQ0106-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-TQ0106-5mg5mg£148.00
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TAR-TQ0106-10mg10mg£201.00
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TAR-TQ0106-25mg25mg£362.00
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TAR-TQ0106-50mg50mg£535.00
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TAR-TQ0106-100mg100mg£740.00
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TAR-TQ0106-500mg500mg£1,428.00
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Further Information

Bioactivity:
Sacubitrilat (LBQ657) is an effective inhibitor of active neprilysin (NEP).
CAS:
149709-44-4
Formula:
C22H23NO5
Molecular Weight:
383.44
Pathway:
Metabolism
Purity:
0.9911
SMILES:
[H]N(C(CCC(O)=O)=O)[C@H](CC(C=C1)=CC=C1C2=CC=CC=C2)C[C@H](C(O)=O)C
Target:
Neprilysin

References

Langenickel TH, et al. Single therapeutic and supratherapeutic doses of sacubitril/valsartan (LCZ696) do not affect cardiac repolarization. Eur J Clin Pharmacol. 2016 Aug;72(8):917-24. Schiering N, et al. Structure of neprilysin in complex with the active metabolite of sacubitril. Sci Rep. 2016 Jun 15;6:27909.