TargetMol

Metyrapone Tartrate

Product Code:
 
TAR-T0293L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T0293L-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
Metyrapone Tartrate is an inhibitor of the STEROID 11-beta-monooxygenase enzyme which is used as a test for feedback hypothalamic-pituitary mechanism in the diagnosis of Cushing SYNDROME.
CAS:
908-35-0
Formula:
C22H26N2O13
Molecular Weight:
526.451
Purity:
0.98
SMILES:
O[C@H]([C@@H](O)C(O)=O)C(O)=O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC(C)(C(=O)c1cccnc1)c1cccnc1

References

1. Weiler U, Finsler S, Claus R. Influence of cortisol, gonadal steroids and an energy deficit on biochemical indicators of bone turnover in Swine. J Vet Med A Physiol Pathol Clin Med. 2003 Mar;50(2):79-87. PubMed PMID: 12667198. 2. Dickstein G, Spindel A, Shechner C, Adawi F, Gutman H. Spontaneous remission in Cushing's disease. Arch Intern Med. 1991 Jan;151(1):185-9. Review. PubMed PMID: 1985595. 3. Mito T, Shiono T, Kimura R, Tamai M. The effect of oral metyrapone on aqueous humor dynamics in normal human eyes. Acta Ophthalmol (Copenh). 1990 Oct;68(5):582-6. PubMed PMID: 2275356. 4. Galinsky RE, Corcoran GB. Suppression of acetaminophen conjugation and of conjugate elimination in the rat by metyrapone, a classical P-450 inhibitor. Drug Metab Dispos. 1988 May-Jun;16(3):348-54. PubMed PMID: 2900724.