TargetMol

CMLD012073

Product Code:
 
TAR-T10848
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10848-5mg5mg£850.00
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Quantity:
TAR-T10848-50mg50mg£1,661.00
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Quantity:
TAR-T10848-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
CMLD012073 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits NIH/3T3 cells (IC50: 10 nM). CMLD012073 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A).
CAS:
2368900-32-5
Formula:
C30H30N2O7
Molecular Weight:
530.577
Purity:
0.98
SMILES:
COC(=O)[C@@H]1[C@@H](c2ccccc2)[C@@]2(Oc3cc(OC)cc(OC)c3[C@@]22NC(C)=N[C@@]12O)c1ccc(OC)cc1

References

1. Chu J, et al. Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors. Cell Chem Biol. 2019 Nov 21;26(11):1586-1593.