TargetMol

Integrin-IN-2

Product Code:
 
TAR-T11663
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11663-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
Integrin-IN-2 is an orally bioavailable pan αv integrin inhibitor.Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively.
CAS:
2378617-67-3
Formula:
C27H30N4O3
Molecular Weight:
458.562
Purity:
0.98
SMILES:
OC(=O)CC(Nc1ccc(OCCc2ccc3CCCNc3n2)cn1)c1cccc(c1)C1CC1

References

1. Anderson NA, et al. Discovery of an Orally Bioavailable Pan ?v Integrin Inhibitor for Idiopathic Pulmonary Fibrosis. J Med Chem. 2019 Oct 10;62(19):8796-8808.