TargetMol

PMX 205

Product Code:
 
TAR-T12506L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T12506L-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
PMX 205 is an effective complement antagonist of the C5a receptor.
CAS:
514814-49-4
Formula:
C45H62N10O6
Molecular Weight:
839.055
Purity:
0.98
SMILES:
[H][C@@]12CCCN1C(=O)[C@]([H])(CCCNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@]([H])(Cc1c[nH]c3ccccc13)NC(=O)[C@@H](CC1CCCCC1)NC2=O)NC(=O)CCc1ccccc1

References

1. Kosni NN, et al. Expression of complement C5a receptor and the viability of 4T1 tumor cells following agonist-antagonist treatment. J Cancer Res Ther. 2016 Apr-Jun;12(2):590-6. 2. Woodruff TM, et al. The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis. J Immunol. 2008 Dec 15;181(12):8727-34. 3. Fonseca MI, et al. Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. J Immunol. 2009 Jul 15;183(2):1375-83.