TargetMol

PNRI-299

Product Code:
 
TAR-T12508
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12508-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).
CAS:
550368-41-7
Formula:
C21H15N5O4
Molecular Weight:
401.382
Purity:
0.98
SMILES:
O=C(NCc1ccccc1)C1=CC(=O)Cn2n1c(=O)n(-c1cccc(c1)C#N)c2=O

References

1. Nguyen C, et al. Chemogenomic identification of Ref-1/AP-1 as a therapeutic target for asthma. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1169-73. 2. Souza DG, et al. NF-kappaB plays a major role during the systemic and local acute inflammatory response following intestinal reperfusion injury. Br J Pharmacol. 2005 May;145(2):246-54.