TargetMol

Prolyl Hydroxylase inhibitor 1

Product Code:
 
TAR-T12547
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12547-5mg5mg£1,010.00
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TAR-T12547-50mg50mg£1,982.00
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Quantity:
TAR-T12547-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
Prolyl Hydroxylase inhibitor 1 is an orally active inhibitor of hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) (IC50 of 62.23 nM).
CAS:
2205125-60-4
Formula:
C19H18ClN5O4
Molecular Weight:
415.83
Purity:
0.98
SMILES:
OC(=O)CNC(=O)c1ncc(cc1O)-c1cn(CCCc2ccc(Cl)cc2)nn1

References

1. Wu Y, et al. Click Chemistry-Based Discovery of [3-Hydroxy-5-(1 H-1,2,3-triazol-4-yl)picolinoyl]glycines as Orally Active Hypoxia-Inducing Factor Prolyl Hydroxylase Inhibitors with Favorable Safety Profiles for the Treatment of Anemia. J Med Chem. 2018 Jun 28;61(12):5332-5349.