TargetMol

Pterosin B

Product Code:
 
TAR-T12576
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12576-5mg5mg£351.00
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TAR-T12576-50mg50mg£1,131.00
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TAR-T12576-100mg100mg£1,669.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pterosin B is an salt-inducible kinase 3 (Sik3) signaling inhibitor. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis by inhibiting Sik3.
CAS:
34175-96-7
Formula:
C14H18O2
Molecular Weight:
218.296
Purity:
0.98
SMILES:
C[C@@H]1Cc2cc(C)c(CCO)c(C)c2C1=O

References

1. Hannah R.Dexter, et al. A concise stereoselective synthesis of pterosin B. Tetrahedron Letters, Volume 59, Issue 49, 5 December 2018, Pages 4323-4325. 2. Yahara Y, et al. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. Nat Commun. 2016 Mar 24;7:10959.