TargetMol

SPR741 acetate (1179330-52-9 free base)

Product Code:
 
TAR-T12992
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12992-1mg1mg£217.00
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TAR-T12992-5mg5mg£444.00
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TAR-T12992-10mg10mg£579.00
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TAR-T12992-25mg25mg£863.00
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TAR-T12992-50mg50mg£1,163.00
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TAR-T12992-100mg100mg£1,540.00
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Further Information

Bioactivity:
SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate.
CAS:
T12992
Formula:
C46H77N13O15
Molecular Weight:
1052.18
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
CC(N[C@@H]([C@H](O)C)C(N[C@H](CO)C(N[C@@H](CCNC([C@](N1)([H])[C@H](O)C)=O)C(N[C@@H](CCN)C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCN)C1=O)=O)CCN)=O)CC(C)C)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O.CC(O)=O
Target:
Antibacterial

References

1. Corbett D, et al. Potentiation of Antibiotic Activity by a Novel Cationic Peptide: Potency and Spectrum of Activity of SPR741. Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00200-17. 2. Eckburg PB, et al. Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, an Intravenous Potentiator, after Single and Multiple Ascending Doses and When Combined with ?-Lactam Antibiotics in Healthy Subjects. Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00892-19.