TargetMol

TAS4464

Product Code:
 
TAR-T13090L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T13090L-5mg5mg£283.00
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TAR-T13090L-1mL1 mL * 10 mM (in DMSO)£308.00
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TAR-T13090L-10mg10mg£417.00
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TAR-T13090L-25mg25mg£764.00
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Quantity:
TAR-T13090L-50mg50mg£1,074.00
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Quantity:
TAR-T13090L-100mg100mg£1,576.00
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This product comes from: United States.
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Further Information

Bioactivity:
TAS4464 is a highly potent and selective inhibitor of the NEDD8 activating enzyme (IC50: 0.955 nM).
CAS:
1848959-10-3
Formula:
C21H23FN6O6S
Molecular Weight:
506.51
Pathway:
Ubiquitination
Purity:
0.9827
SMILES:
CCOc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12
Target:
E1/E2/E3 Enzyme

References

1. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.