TargetMol

Top1 inhibitor 1

Product Code:
 
TAR-T13183
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13183-5mg5mg£850.00
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Quantity:
TAR-T13183-50mg50mg£1,661.00
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Quantity:
TAR-T13183-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Top1 inhibitor 1 is a potent inhibitor of human topoisomerase I (Top1)(IC50: 29 nM).
CAS:
2302772-05-8
Formula:
C24H22N6O2
Molecular Weight:
426.48
Purity:
0.98
SMILES:
COc1ccc(cc1)-c1ccc2ncc(-c3nnco3)c(NCCCn3ccnc3)c2c1

References

1. Kundu B, et al. Discovery and Mechanistic Study of Tailor-Made Quinoline Derivatives as Topoisomerase 1 Poison with Potent Anticancer Activity. J Med Chem. 2019 Apr 11; 62(7):3428-3446.