TargetMol

TP3011

Product Code:
 
TAR-T13191
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T13191-5mg5mg£1,653.00
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Quantity:
TAR-T13191-50mg50mg£3,267.00
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Quantity:
TAR-T13191-100mg100mg£4,488.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
TP3011 is a potent topoisomerase I inhibitor equipotent as SN38 and is an active metabolite of CH-0793076.
CAS:
534605-74-8
Formula:
C26H26N4O5
Molecular Weight:
474.517
Purity:
0.98
SMILES:
CCCCCn1c2c3Cn4c(cc5c(COC(=O)[C@]5(O)CC)c4=O)-c3nc3cccc([nH]c1=O)c23

References

1. Anthoney DA, et al. Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses.BMC Cancer. 2012 Nov 21;12:536. 2. Niizuma S, et al. Synthesis of new camptothecin analogs with improved antitumor activities.Bioorg Med Chem Lett. 2009 Apr 1;19(7):2018-21.