TargetMol

VBIT-3

Product Code:
 
TAR-T13286
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13286-5mg5mg£850.00
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TAR-T13286-50mg50mg£1,661.00
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Quantity:
TAR-T13286-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
VBIT-3 is a voltage-dependent anion channel 1 (VDAC1) oligomerization inhibitor (Kd: 31.3 μM). VBIT-3 also is an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders (such as neurodegenerative and cardiovascular diseases).
CAS:
2088463-66-3
Formula:
C21H19ClF3N3O3
Molecular Weight:
453.85
Purity:
0.98
SMILES:
FC(F)(F)Oc1ccc(cc1)N1CCN(CC1)C1CC(=O)N(C1=O)c1ccc(Cl)cc1

References

1. Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.