TargetMol

Afabicin

Product Code:
 
TAR-T14134
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14134-5mg5mg£370.00
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Quantity:
TAR-T14134-50mg50mg£1,356.00
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Quantity:
TAR-T14134-100mg100mg£2,022.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Afabicin is the prodrug of Debio1452. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
CAS:
1518800-35-5
Formula:
C23H24N3O7P
Molecular Weight:
485.433
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
CN(Cc1oc2ccccc2c1C)C(=O)C=Cc1cnc2N(COP(O)(O)=O)C(=O)CCc2c1
Target:
Antibacterial

References

1. Flamm RK, et al. Activity of Debio1452, a FabI inhibitor with potent activity against Staphylococcus aureus and coagulase-negative Staphylococcus spp., including multidrug-resistant strains. Antimicrob Agents Chemother. 2015 May;59(5):2583-7.