TargetMol

Lacidipine

Product Code:
 
TAR-T1439
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1439-10mg10mg£107.00
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TAR-T1439-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T1439-25mg25mg£129.00
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TAR-T1439-50mg50mg£148.00
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TAR-T1439-100mg100mg£197.00
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TAR-T1439-200mg200mg£266.00
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Further Information

Bioactivity:
Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure.
CAS:
103890-78-4
Formula:
C26H33NO6
Molecular Weight:
455.551
Pathway:
Membrane transporter/Ion channel; Immunology/Inflammation; NF-κb; Apoptosis; Metabolism
Purity:
0.9985
SMILES:
CCOC(=O)C1=C(C)NC(C)=C(C1c1ccccc1C=CC(=O)OC(C)(C)C)C(=O)OCC
Target:
Apoptosis; Calcium Channel; Reactive Oxygen Species

References

1. Wang F, et al. Chem Biol,2011, 18(6), 766-776. 2. Bernini F, et al. Br J Pharmacol,1997, 122(6), 1209-1215. 3. Kyselovic J, et al. Br J Pharmacol,2001, 134(7), 1516-1522. 4. Halici Z, et al. Eur J Pharmacol,2008, 579(1-3), 241-245. 5. Feron O, et al. Br J Pharmacol,1996, 118(3), 659-664.