TargetMol

GSK3395879

Product Code:
 
TAR-T15439
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15439-5mg5mg£1,171.00
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Quantity:
TAR-T15439-50mg50mg£2,303.00
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Quantity:
TAR-T15439-100mg100mg£3,042.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).
CAS:
2215852-91-6
Formula:
C20H15F4N3O5S
Molecular Weight:
485.41
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(cc1C#N)C(F)(F)F
Target:
TRP/TRPV Channel

References

1. Brnardic EJ, et al. Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4). J Med Chem. 2018 Nov 8;61(21):9738-9755.