TargetMol

Mdivi-1

Product Code:
 
TAR-T1907
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1907-5mg5mg£103.00
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TAR-T1907-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T1907-10mg10mg£114.00
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TAR-T1907-25mg25mg£148.00
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TAR-T1907-50mg50mg£197.00
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TAR-T1907-100mg100mg£264.00
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Quantity:
TAR-T1907-200mg200mg£361.00
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This product comes from: United States.
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Further Information

Bioactivity:
Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) (IC50: 1-10 μM).
CAS:
338967-87-6
Formula:
C15H10Cl2N2O2S
Molecular Weight:
353.22
Pathway:
Autophagy; Apoptosis; Cytoskeletal Signaling
Purity:
0.9864
SMILES:
COc1cc(c(Cl)cc1Cl)-n1c(S)nc2ccccc2c1=O
Target:
Apoptosis; Mitophagy; Dynamin; Autophagy

References

1. Cassidy-Stone A, et al. Dev Cell, 2008, 14(2), 193-204. 2. Park SW, et al. Invest Ophthalmol Vis Sci, 2011, 52(5), 2837-2843. 3. Su Q, Wang J, Liu F, et al. Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis[J]. Toxicology in Vitro. 2020: 104840.