TargetMol

LDN-57444

Product Code:
 
TAR-T1924
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T1924-2mg2mg£98.00
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Quantity:
TAR-T1924-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T1924-5mg5mg£111.00
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TAR-T1924-10mg10mg£144.00
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Quantity:
TAR-T1924-25mg25mg£212.00
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Quantity:
TAR-T1924-50mg50mg£322.00
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Quantity:
TAR-T1924-100mg100mg£461.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .
CAS:
668467-91-2
Formula:
C17H11Cl3N2O3
Molecular Weight:
397.64
Pathway:
Ubiquitination; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Apoptosis
Purity:
0.9987
SMILES:
CC(=O)ON=C1/C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Cl)cc12
Target:
Apoptosis; DUB

References

1. Liu Y, et al. Chem Biol, 2003, 10(9), 837-846. 2. Cartier AE, et al. PLoS One, 2012, 7(4), e34713. 3. Gong B, et al. Cell, 2006, 126(4), 775-788. 4. Tan YY, et al. Mol Cell Biochem, 2008, 318(1-2), 109-115.