TargetMol

8-Azahypoxanthine

Product Code:
 
TAR-T20102
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20102-5mg5mg£111.00
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Quantity:
TAR-T20102-1mL1 mL * 10 mM (in DMSO)£112.00
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Quantity:
TAR-T20102-10mg10mg£131.00
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TAR-T20102-25mg25mg£173.00
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TAR-T20102-50mg50mg£225.00
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Quantity:
TAR-T20102-100mg100mg£301.00
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Quantity:
TAR-T20102-200mg200mg£417.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
8-Azahypoxanthine inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.
CAS:
2683-90-1
Formula:
C4H5N5O
Molecular Weight:
139.118
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
ON1CN=Cc2[nH]nnc12
Target:
Nucleoside Antimetabolite/Analog

References

1. Volchkov VA, Mikha?lova NIa. Radiomodifitsiruiushchee de?stvie 8-azagipoksantina [Radiomodifying action of 8-azahypoxanthine]. Radiobiologiia. 1984 Jan-Feb;24(1):90-2. Russian. 2. Keough DT, et al. Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases. J Med Chem. 2006 Dec 14;49(25):7479-86. 3. Moore BC, Leigh JA. Markerless mutagenesis in Methanococcus maripaludis demonstrates roles for alanine dehydrogenase, alanine racemase, and alanine permease. J Bacteriol. 2005 Feb;187(3):972-9. 4. Groom J, et al. Promiscuous plasmid replication in thermophiles: Use of a novel hyperthermophilic replicon for genetic manipulation of Clostridium thermocellum at its optimum growth temperature. Metab Eng Commun. 2016 Jan 29;3:30-38.